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BARDA Chem and RadNuc Animal Model Development

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The Biomedical Advanced Research and Development Authority (BARDA) has issued a notice seeking laboratory research services to establish new or existing animal models for the development of Chemical and Radiological/Nuclear Medical Countermeasures (MCMs).

BARDA anticipates that contracts awarded from effort will serve to facilitate the animal model development of medical countermeasures and supportive reagents and assays for regulatory acceptance in the U.S.

In these models, the challenge dose generally should be the same as that which produces the human disease or condition and the pathophysiological mechanism of its toxicity should be reasonably well-understood and mimic the human condition as closely as possible.

When these models are used to test the efficacy of potential MCMs for threat agents, the mechanism of action of the countermeasure will need to establish the utility of the animal model as a surrogate for humans.

It is anticipated that the official RFP will be released January 20, 2015, with proposals being due on or about March 4, 2015. Multiple awards may result from this solicitation with an estimated award date in July 2015.

Further details are available under Solicitation Number: RFP-15-100-SOL-00004.

Editor’s Note: The release date for the RFP was postponed until on/about Mar 17, 2015.

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