NIAID Pandemic Preparedness Plan Aims to Bolster Studies for ‘Prototype’ Pathogens
According to the National Institute of Allergy and Infectious Diseases' new Pandemic Preparedness Plan, the institute will direct its preparedness ...
Tag: Animal Models
First Lethal Hamster Model for SARS-CoV-2 Developed by USAMRIID Scientists
This model system will aid in understanding the severe disease course of COVID-19—including the virus’s interaction with the central nervous ...
Complete Protection Against Yersinia pestis by Immunization with Inhalable rF1-V10 Fusion Protein
The capsular antigen F1, the low-calcium-response V antigen (LcrV), and the recombinant fusion protein (rF1-LcrV) of Yersinia pestis, are leading ...
Preclinical Studies Support Army’s Pan-Coronavirus Vaccine Development Strategy
Pre-clinical studies published today in Science Translational Medicine indicate that the SpFN vaccine protects non-human primates from disease caused by ...
How Well Do Covid Vaccines Hold Up Over Time? Macaque Study Shows Decline in Lung Protection
The findings point to the need for mRNA-1273 booster vaccination to sustain high-level and rapid protection in the lung and ...
Moderna COVID Booster Study in Rhesus Macaques Shows Increased Antibody Response
NIH researchers evaluated the immune responses in nonhuman primates that received a primary vaccination series of mRNA-1273 (Moderna) and were ...
Soligenix COVID-19 Vaccine Demonstrates Efficacy in Non-Human Primates
Vaccination yields broad neutralizing antibody responses against original strain and Beta, Gamma and Delta variants CiVax™ is under development as ...
Macaques Develop Promising Immune Response to SARS-CoV-2
In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 ...
Results of Comprehensive SARS-CoV-2 Non-Human Primate Study Published
Scientists at Texas Biomedical Research Institute and Southwest National Primate Research Center (SNPRC) published their findings regarding a comprehensive animal ...
Stopping Lethal Lung Damage from Influenza: MG53 Protein Shows Promise in Animal Models
The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a ...
High Dose Favipiravir Countered SARS-CoV-2 in Hamsters, Hydroxychloroquine Ineffective
Virologists at the Rega Institute have shown that the anti-malaria drug hydroxychloroquine does not limit SARS-CoV-2 coronavirus replication in hamsters. ...
NIH Funds a $9.3M Center for Precision Animal Modeling at UAB
Precision disease modeling involves creation of patient-specific disease models that mimic the molecular character of a condition present in a ...
USAMRIID Scientists Engineer First Lethal Mouse Model for COVID-19
Small animal models mirroring human disease are essential for advancing vaccines, diagnostics, and treatments to combat emerging pathogens. Army scientists ...
Thailand Begins Coronavirus Vaccine Trials on Monkeys
Thailand’s National Vaccine Institute (NVI) at Chulalongkorn University today began testing a trial vaccine against the novel coronavirus on non-human ...
Macaques Show Protective Immunity Against SARS-Cov-2 After Infection or Vaccine
An understanding of protective immunity to SARS-CoV-2 is critical for vaccine and public health strategies. A key unanswered question is ...
‘Dirty Mice’ Could Help Make a More Effective Flu Vaccine
Study suggests standard laboratory mice may lead scientists to overestimate vaccine efficacy. A new study calls into question the reliance ...
Investigational Chimp Adenovirus MERS-CoV Vaccine Protects Monkeys
An investigational vaccine called ChAdOx1 MERS protected two groups of rhesus macaques from disease caused by Middle East respiratory syndrome ...
Virus Shedding in Rhesus Macaques Innoculated with SARS-CoV-2
Certain aspects of the pathogenesis of SARS-CoV-2 can only be studied in detail in animal models, where repeated sampling and ...
Tulane National Primate Research Center Launches Coronavirus Research Program
From working to develop one of the first nonhuman primate models for the 2019 novel coronavirus disease (COVID-19) to designing ...
Study Shows Virulence of B. pseudomallei Strain in Aerosol Model
Burkholderia pseudomallei, the aetiological agent of melioidosis, causes a serious and often fatal disease in humans and animals. Novel medical ...
