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Home CBRNE

RFI – Bioscavenger Medical Countermeasures

by Global Biodefense Staff
January 29, 2016
Nerve Agent Countermeasures

The U.S. Department of Defense is seeking information from organizations on their capability to support advanced development of human butyrylcholinesterase (HuBChE) as a medical countermeasure.

Overseen by the Joint Product Manager – Medical Countermeasure Systems (JPM-MCS) and executed by the prime contractor Dynport Vaccine Company LLC (DVC), a subcontractor is sought to perform half maximal inhibitory concentration (IC50) determinations for Guinea Pig, Rhesus Macaque and Human Erythrocyte-associated Acetylcholinesterase (AChE) exposed to organophosphate nerve agents (GD and VX).

Respondents must have appropriate safety practices in place to handle organophosphate nerve agents; demonstrated ability to perform in vitro enzyme inhibition studies; and the demonstrated ability to produce data and documentation for submission to the FDA in support of product licensure.

Further details are available via Solicitation Number: W911QY-16-S-0001. The response deadline is February 12, 2016.

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Tags: BioscavengersJPEO-CBRNDRFI

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