Thursday, January 26, 2023
News on Pathogens and Preparedness
Global Biodefense
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe
No Result
View All Result
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe
No Result
View All Result
Global Biodefense
No Result
View All Result
Home Industry News

Navrogen Enters CRADA with USAMRIID to Test Small Molecule NK Cell Activators Against SARS-COV-2 Infection

by Global Biodefense Staff
September 13, 2021
Patients in Nebraska Part of First COVID-19 Clinical Trial in U.S.

USAMRIID will test Navrogen’s NAV-201 small molecule against SARS-COV-2 infected human epithelial cells in vitro and in in vivo rodent studies

Navrogen, Inc. has entered into a Cooperative Research and Development Agreement (CRADA) with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) at Fort Detrick, Md. The CRADA is focused on testing Navrogen’s small molecule NK cell activating agents on suppressing propagation of SARS-COV-2.

The company announced the research partnership on Sep. 13.

Researchers at USAMRIID have developed model systems to test agents capable of suppressing SARS-COV-2 infection and propagation. Navrogen has assembled a pipeline of compounds that are able to activate human and rodent NK cells to stimulate humoral immune responses and target cell killing of dysregulated cells.

Under this CRADA, USAMRIID will test Navrogen’s NAV-201 small molecule against SARS-COV-2 infected human epithelial cells in vitro and in in vivo rodent studies. This approach offers opportunities to address viral infection and propagation regardless of strain genotype.

“We are pleased to have USAMRIID as a partner to test the utility of our NK cell activating agents against viral disease as we advance our humoral immune enhancing agents towards clinical development,” stated Nicholas Nicolaides, Chief Executive Officer at Navrogen. “The expertise of USAMRIID researchers in testing our agents to combat infectious diseases offers the best opportunity to evaluate compounds with new modes of anti-viral activity.”

Source: Navrogen, adapted.

Tags: AntiviralsEditor PickSARS-CoV-2USAMRIID

Related Posts

DARPA Selects Teams to Develop Vaccine Durability Prediction Model
Medical Countermeasures

DARPA Selects Teams to Develop Vaccine Durability Prediction Model

January 13, 2023
small glass vials on an assembly line await filling of vaccine solution
Industry News

Sabin Vaccine Institute to Advance Ebola Sudan and Marburg Vaccines with New BARDA Funding

January 12, 2023
How Are Bivalent COVID Vaccines Stacking Up Against Omicron?
Infectious Diseases

How Are Bivalent COVID Vaccines Stacking Up Against Omicron?

January 12, 2023
NISTCHO: New Living Reference Material for Producing Monoclonal Antibodies
Medical Countermeasures

NISTCHO: New Living Reference Material for Producing Monoclonal Antibodies

January 12, 2023
Load More

Latest News

Partner Therapeutics’ Novel Approach to Stratify Sepsis Patients Gains Backing From BARDA

Biopreparedness Research Virtual Environment (BRaVE) Initiative Backed by $105M DOE Funding

January 25, 2023
Influenza Proteins Tilt and Wave in ‘Breath-like’ Motions

Influenza Proteins Tilt and Wave in ‘Breath-like’ Motions

January 25, 2023
Biodefense Headlines – 24 January 2023

Biodefense Headlines – 24 January 2023

January 24, 2023
Biodefense Headlines – 17 January 2023

Biodefense Headlines – 17 January 2023

January 17, 2023

Subscribe

  • About
  • Contact
  • Privacy
  • Subscribe

© 2022 Stemar Media Group LLC

No Result
View All Result
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe

© 2022 Stemar Media Group LLC

We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are okay with it.OkPrivacy policy