The U.S. Army Edgewood Chemical Biological Center (ECBC) is seeking contract development of monoclonal antibodies to tetrodotoxin, an extremely potent toxin found mainly in the liver and gonads of some fish, amphibian, octopus, and shellfish species.
The government is seeking all personnel, equipment, tools, materials, supervision, and non-personal services necessary to support antibody development form immunogen synthesis through cloning. The four clones with the best sensitivity to tetrodotoxin in a dose response assay will be isolated and grown to confluence resulting in 40 mL of supernatant containing maximally expressed monoclonal antibody.
This supernatant from each of the final four clones will be delivered to the customer for comparison assessments of sensitivity, specificity and possible matrix interferences in assay development.
Further details are available at Solicitation Number: W91ZLK-15-T-0236. The response deadline is July 24, 2015.
