Ebola

Ebola disease is a severe, often fatal illness caused by infection with Orthoebolavirus species, notably Ebola virus (EBOV), Sudan virus (SUDV), and Bundibugyo virus (BDBV). These viruses are classified as Select Agents due to their high lethality, potential for person-to-person transmission, and use in bioterrorism scenarios. The average case fatality rate is around 50%, with some outbreaks reaching up to 90%.

Transmission occurs through direct contact with infected bodily fluids or contaminated materials. Human outbreaks often begin through zoonotic spillover from infected wildlife such as fruit bats or primates.