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The Impact of Vector-Borne Diseases on Global Health

Vector-Borne Global HealthThe National Academies of Science, Engineering and Medicine (NASEM) Forum on Microbial Threats has released a new summary of its most recent workshop exploring the dynamic relationships among host, pathogens, vectors, and ecosystems that characterize vector-borne diseases.

The Forum revisited the trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats.

Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation.

Content chapters include:

  • Emerging Insect-Transmitted Plant Diseases: The Bacterium Xylella fastidiosa as a Case Study
  • Genetic Control of Aedes Mosquitoes
  • The Intensifying Storm: Domestication of Aedes aegypti, Urbanization of Arboviruses, and Emerging Insecticide Resistance
  • Dengue, Chikungunya, and Other Vector-Borne Diseases (VBDs): Surveillance and Response in Latin America and the Caribbean: The Role of the Pan American Health Organization
  • Vector-Borne Diseases: Animals and Patterns
  • Drivers, Dynamics, and Control of Emerging Vector-Borne Zoonotic Diseases
  • Climate Teleconnections, Weather Extremes, and Vector-Borne Disease Outbreaks
  • Changing Paradigms for Tick-Borne Diseases in the Americas
  • Emerging Vector-Borne Diseases in the United States: What Is Next, and Are We Prepared?
  • Arbovirus Evolution, Vector Competence, and Virulence Models – Changing Patterns of Infection
  • Vector-Borne Disease Emergence and Spread in the European Union
  • Disruption of Insect Transmission of Plant Viruses

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases – including malaria, dengue, yellow fever, and plague – together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined.

Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans.

Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls.

Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future.

Read more: Global Health Impacts of Vector-Borne Diseases: Workshop Summary (2016)

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