Thursday, January 26, 2023
News on Pathogens and Preparedness
Global Biodefense
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe
No Result
View All Result
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe
No Result
View All Result
Global Biodefense
No Result
View All Result
Home Infectious Diseases

Study Finds One Third of Cambodians Infected with Threadworm

by Global Biodefense Staff
June 20, 2019
Strongyloides stercoralis

Larva of nematode parasite Strongyloides stercoralis cause of strongyloidiasis. Credit: CDC

Strongyloides stercoralis is a soil-transmitted threadworm that is endemic in many tropical and subtropical areas of the world. Now, researchers reporting in PLOS Neglected Tropical Diseases have conducted a nation-wide parasitology survey of the Cambodian population and concluded that nearly a third of the studied population is infected with S. stercoralis.

The threadworm is transmitted through infected larvae in the soil and, like hookworms, infect humans through the skin. The worm can cause long-lasting and potentially fatal infections in people. Larvae are not detected by standard coprological diagnostics, so S. stercoralis has been under-detected and overlooked for decades.

In the new work, Peter Odermatt, of the Swiss Tropical and Public Health Institute, and colleagues used a diagnostic test that detects S. stercoralis IgG antibodies in the urine. 7,246 enrolled study participants took the test and provided data on demography, hygiene, and knowledge about helminth infection.

Overall, 30.5% of participants were infected with threadworms. The rate in individual provinces ranged from 10.9% to 48.2%, with prevalence rates below 20% in only five south-eastern provinces. The risk of infection increased with age, and open defecation was associated with a higher risk while knowledge about helminth infections lowered a person’s risk. In addition, S. stercoralis infection was positively associated with night temperatures, rainfall and distance to water, and negatively associated with land occupied by rice fields. Advanced spatial statistical modeling allowed predicting S. stercoralis in unsurveyed locations, which lead to a unique result, namely a country-wide risk profile for S. stercoralis infection in Cambodia.

“Our study represents a clear risk map of S. stercoralis of a highly endemic setting,” the researchers say. “Based on these data the population at risk can be quantified and planning of concrete control approach become realistic.” Subsidies to support the high cost of drugs, or affordable generics, are needed to start tackling the worm, they add.

Forrer A, Khieu V, Vounatsou P, Sithithaworn P, Ruantip S, et al. (2019) Strongyloides stercoralis: Spatial distribution of a highly prevalent and ubiquitous soil-transmitted helminth in Cambodia. PLOS Neglected Tropical Diseases 13(6): e0006943. https://doi.org/10.1371/journal.pntd.0006943

Tags: Editor PickNeglected Tropical Diseases

Related Posts

How Are Bivalent COVID Vaccines Stacking Up Against Omicron?
Infectious Diseases

How Are Bivalent COVID Vaccines Stacking Up Against Omicron?

January 12, 2023
Officials Declare End to Ebola Outbreak in Uganda
Infectious Diseases

Officials Declare End to Ebola Outbreak in Uganda

January 11, 2023
Why Upper Respiratory Infectious are More Common in Colder Temperatures
Infectious Diseases

Why Upper Respiratory Infectious are More Common in Colder Temperatures

December 7, 2022
runners on a track
Infectious Diseases

Feeling Winded After Your Workout? Long COVID May Reduce Exercise Capacity

October 23, 2022
Load More

Latest News

Partner Therapeutics’ Novel Approach to Stratify Sepsis Patients Gains Backing From BARDA

Biopreparedness Research Virtual Environment (BRaVE) Initiative Backed by $105M DOE Funding

January 25, 2023
Influenza Proteins Tilt and Wave in ‘Breath-like’ Motions

Influenza Proteins Tilt and Wave in ‘Breath-like’ Motions

January 25, 2023
Biodefense Headlines – 24 January 2023

Biodefense Headlines – 24 January 2023

January 24, 2023
Biodefense Headlines – 17 January 2023

Biodefense Headlines – 17 January 2023

January 17, 2023

Subscribe

  • About
  • Contact
  • Privacy
  • Subscribe

© 2022 Stemar Media Group LLC

No Result
View All Result
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe

© 2022 Stemar Media Group LLC