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Home Biosurveillance

USF Study: COVID-19 Possibly Striking More Children Than Expected

by Global Biodefense Staff
April 17, 2020
The Challenges of Developing a Safe and Effective COVID-19 Vaccine

Novel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles (orange), isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

The number of children infected with the coronavirus is far more extensive than what is currently reported — a hidden detail that could vastly underestimate the demand on health care systems and pediatric intensive care units (PICUs).

A new study published in the “Journal of Public Health Management and Practice” from the University of South Florida (USF) and the Women’s Institute for Independent Social Enquiry (WiiSE), estimates that for each child who requires intensive care for COVID-19, there are 2,381 children infected with the virus. This calculation follows a report from the Chinese Center for Disease Control and Prevention regarding its clinical study of over 2,100 children in China with COVID-19.

According to the North American registry, Virtual PICU Systems, 74 children in the U.S. were admitted to PICUs between March 18 and April 6, signaling an additional 176,190 children were likely infected during this timeframe. Children younger than 2 accounted for 30 percent of the cases, 24 percent were ages 2 to 11 and 46 percent of the PICU cases were children between ages 12 and 17.

Cumulative number of confirmed COVID-19 pediatric intensive care patients United States (Mar 18-Apr 6) Credit: mvps.org

Researchers say that if as many as 25 percent of the U.S. population becomes infected with the coronavirus before the end of 2020, 50,000 children with severe illness will need to be hospitalized, with 5,400 of them critically ill and requiring mechanical ventilation. Clinical reports indicate the average length of stay for pediatric COVID-19 is 14 days. According to a national survey aimed to evaluate the U.S. pediatric critical care capacity and published in “Critical Care Medicine,” there are approximately 5,100 PICU beds in the U.S.

Cumulative estimated number of children infected with SARS-CoV-2 United States. (March 18-April 6). Credit: USF

“Although the risk of severe illness from COVID-19 is lower in pediatric cases than adults, hospitals should be prepared and have the proper equipment and staffing levels to deal with a potential influx of younger patients,” said author Jason Salemi, associate professor of epidemiology in the USF College of Public Health. “Government officials and policy makers should understand the likelihood of capacity challenges, which underscores the importance of effective mitigation strategies such as frequent and thorough handwashing and persisted social distancing measures.”

Projected numbers of children aged 0 to 17 years in the United States who will require hospitalization for COVID-19 during 2020. Credit: USF

Pediatric coronavirus is highly complex, as many hospitals are prohibiting visitors in order to implement social distancing and quarantine protocols. A caretaker may also be infected, which would require logistical and infection control accommodations that place an additional strain on hospital resources. Upon hospital discharge, young children may be unable to independently comply with home infection control and self-isolation recommendations.

Researchers point out the infection rate will be much higher for children in low-income families with parents in blue-collar and service jobs, which preclude the option of working from home. There’s also an increased risk to children who live in urban public housing projects due to the close proximity of housing units and small communal recreation and commons areas.

Intensive Care Admissions, Estimated Total Infected, and Projected Numbers of Severe Pediatric Cases in 2020. Journal of Public Health Management & Practice, Published online 16 April 2020.

Tags: COVID-19Editor PickEpidemiologySARS-CoV-2Virology

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