New research from the US has shown that white-tailed deer are being infected with SARS-CoV-2, the virus that causes COVID-19 in humans. Antibodies were found in 40% of deer that were tested from January to March 2021 across Michigan, Pennsylvania, Illinois and New York state. A second unpublished study has detected the virus in 80% of deer sampled in Iowa between November 2020 and January 2021.
Such high levels of infection led the researchers to conclude that deer are actively transmitting the virus to one another. The scientists also identified different SARS-CoV-2 variants, suggesting there have been many human-to-deer infections.
The large numbers of white-tailed deer in North America and the fact that they often live close to people provide several opportunities for the disease to move between the two species. This can include wildlife management operations, field research, recreation, tourism and hunting. In fact, hunters are likely to be one of the most obvious sources of potential reinfection as they regularly handle dead animals. It has also been suggested that water sources contaminated with SARS-CoV-2 might provide a pathway for transmission, although this has yet to be proved.
Human-to-deer and deer-to-deer transmission are believed to be driving the rapid spread of the disease within white-tailed deer populations across the US. This is particularly apparent during the early months of 2021 when COVID infections were spiking in the human population. Previous studies have shown that SARS-CoV-2 can be passed from humans to domestic and captive animals including cats, dogs, zoo animals and, most notably, farmed mink. But, until now, the disease had not been shown to spread in wildlife species.
White-tailed deer are the most abundant large mammal in North America with a range extending from Canada to South America. The US population alone is estimated to number 30 million animals. They are a social species that live in family groups of two to 12 individuals that can thrive in a range of habitats, including urban parks and woodland.
These aspects of their ecology and behaviour have made them a species of particular concern when it comes to the spread of diseases, including bovine tuberculosis and chronic wasting disease. These pathogens have already led to considerable effects on the health of wild and domestic animal populations around the globe.
The findings from these latest studies have raised concerns that white-tailed deer could be a reservoir of SARS-CoV-2. Not only could this readily infect large numbers of animals, but also, more worryingly, it could spill back to humans.
This type of infection cycle was documented in workers on infected mink farms, which ultimately led to the Danish government euthanising their entire captive population of 17 million animals. It is important to underline that there is currently no evidence of SARS-CoV-2 transmission from white-tailed deer to humans. Initial experimental work has also suggests that infected deer tend not to have symptoms. Still, disease transmission in wildlife populations has considerable implications for human and animal health.
Potential Source of New Variants
There is the possibility that viral mutation in a reservoir host, such as white-tailed deer, could lead to new variants of the disease. These variants may lead to greater infection rates, increased virulence (severity of symptoms) and prove more effective at evading the human immune system. Likewise, any reinfection from wildlife reservoirs could also complicate our long-term efforts to fight and suppress the disease.
Influenza, which jumps readily between birds, humans and other mammals (particularly pigs), presented similar problems. These multiple reservoirs of disease can lead to new strains emerging that humans have lower immunity against, as was the case with swine flu in 2009.
It is important to note that there are limitations to these studies, both in terms of the methods used and the limited geographical range of investigation. The most recent and unpublished study used the latest genetic approaches to reliably detect SARS-CoV-2 in tissue samples but focused only on deer in Iowa. Whereas the antibody tests in the first study were conducted across four states but only show that the animal has been exposed to the virus. Yet the combined findings have highlighted that transmission of SARS-CoV-2 is likely to be widespread in white-tailed deer.
There is a great deal that we still need to learn about the developing situation with COVID and deer. The most important topics to focus on include understanding how the virus is being transmitted from humans to deer and determining the risk of spillover back into the human population. Research is urgently needed to assess the risk that this potential reservoir of SARS-CoV-2 presents to humans, as well as the possible spread of the virus to other wildlife species that deer interact with, such as predators and scavengers.
ABOUT THE AUTHORS
Graeme Shannon, Lecturer in Zoology, Bangor University. My research interests are wide-ranging and involve exploring questions in the fields of behavioural ecology and conservation. These include studying the foraging, movement ecology and cognitive behaviour of African elephants, as well as the behavioural responses of wildlife to anthropogenic noise exposure. I am also interested in the role that large herbivores play in ecosystem function, and more generally, exploring how human activities affect animals at both the individual and population level.
Amy Gresham, PhD Student, Behavioural Ecology, Bangor University. My research background is in behavioural ecology, with an interest in how animals respond to changes in their environment and the implications this has for conservation. Following completion of an MSc in Conservation & Biodiversity from the University of Exeter, I began studying for my PhD at Bangor University in 2018, funded by the Envision Doctoral Training Programme (NERC). My PhD focuses on linking the behaviour of an expanding population of fallow deer (Dama dama) to their effects on woodlands in the Elwy Valley, North Wales. The aim of the project is to establish how deer woodland occupancy is influenced by habitat structure and resource availability. Deer occupancy data will come from camera traps, while terrestrial laser scans, tree stand surveys and ground flora surveys will provide information on habitat structure and seasonal resources. Additionally, seasonal dietary analysis will be carried out to investigate how diet composition varies throughout the year and whether this is linked to seasonal variation in resource availability and diversity.
Owain Barton, PhD Student, Ecology, Bangor University. The scope of my research is broad and explores a variety of topical issues including wildlife resource-use, population dynamics and movement ecology. I will be observing a largely isolated population of Fallow deer (Dama dama) in North Wales using GPS collars, drone-mounted thermal imaging cameras and motion-activated camera traps. I intend to identify the landscape-scale drivers of resource-use and observe behavioural responses to anthropogenic disturbance. The project is supported by a KESS 2 scholarship and will operate in collaboration with the Game & Wildlife Conservation Trust to inform sustainable ungulate management.
This article is courtesy of The Conversation.