Are systemic reactions more common after simultaneous administration of COVID-19 mRNA booster and seasonal influenza vaccines than after COVID-19 mRNA booster alone?
Findings from this study suggest that simultaneous administration of COVID-19 mRNA booster and influenza vaccines may be associated with a slightly increased likelihood of systemic reactions.
Self-reported data from 981,099 persons aged 12 years or older given simultaneous administration of a COVID-19 mRNA booster dose and an influenza vaccine was associated with 8% to 11% increases, respectively, in systemic reaction compared with COVID-19 mRNA booster alone.
In both groups, most reactions reported in the week following vaccination were generally mild.
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