Assessing the Burden and Potential Strategies to Address Antimicrobial Resistance

A National Academies’ committee of experts will convene 4-5 March 2024 for a workshop to discuss the burden of antimicrobial resistance and strategies to address AMR challenges.

Participants can attend the workshop virtually and submit questions to speakers. The event will take place 12:00 PM – 4:15 PM ET each day.

There is broad recognition of the critical need to address the development and spread of antimicrobial resistance (AMR). A global, systematic analysis estimates that AMR infections lead to 1.27-4.95 million deaths per year, and resistant bacterial infections are now a leading cause of neonatal mortality worldwide. While scientific and economic challenges have long hindered development of novel antimicrobials, recent pull incentives have been proposed to support a sustainable market and investment in new antimicrobials. These recent discussions provide a timely opportunity to explore the current burden of AMR and discuss potential future policies in the context of new scientific innovations.

Highlighted agenda topics include:

Monitoring AMR in Plants, Animals, and the Environment

• Moderator: Ramanan Laxminarayan, One Health Trust
• Environmental and Wastewater Surveillance: Joakim Larsson, University of Gothenburg
• AMR in Livestock and Food Systems (or Crops): Paul Plummer, Iowa State University College of Veterinary Medicine
• Role of AMR in Cross-cutting Conferences – Experience from COP28: Haileyesus Getahun, World Health Organization

Making Meaning from Metrics: What’s at Stake?

• Moderator: Chris Braden, U.S. Centers for Disease Control and Prevention
• Impact of AMR – what’s not being captured: Dawn Sievert, U.S. Centers for Disease Control and Prevention
• Modeling Prevention Strategies: Joseph Lewnard, University of California, Berkeley

Impact of AMR Across Medical Practice

• Moderator: Helen Boucher, Tufts University
• Skilled Nursing Facilities: Susan Huang, University of California, Irvine
• Surgery: Shawn Rangel, Boston Children’s Hospital
• Oncology: John Wingard, University of Flo

Stewardship

• Outpatient or Telemedicine Perspective: Kristin Ray, UPMC Children’s Hospital of Pittsburgh
• Advanced Diagnostics: Robin Patel, Mayo Clinic
• Pediatric Antimicrobial Stewardship (Hospital Perspective): Ritu Banerjee, Vanderbilt University Medical Center

Access

• Protecting Pharmaceutical Supply Chains in LMICs: Anthony McDonnell, Center for Global Development
• Improving Access and Balancing Stewardship in LMICs: Jennifer Cohn, Global Antibiotic Research & Development Partnership
• Sustainable Use of Available Medicines: Esmita Charani, University of Cape Town

Innovation

• Synthetic Biology and Artificial Intelligence: James Collins, Massachusetts Institute of Technology
• Considerations for Successful Public-Private Partnership Model in Antibiotic Development: Ken Duncan, Bill & Melinda Gates Foundation
• Supporting New Antimicrobials in Clinical Use: Ramy Elshaboury, Massachusetts General Hospital

Please visit NASEM’s Assessing the Burden and Potential Strategies to Address Antimicrobial Resistance: A Workshop for more information.