The University of Texas Medical Branch at Galveston, Profectus Biosciences, Tekmira Pharmaceuticals and the Vanderbilt University Medical Center have been awarded up to $26 million to advance treatments of the highly lethal hemorrhagic fever viruses Ebola and Marburg.
These filoviruses are considered “Tier 1″ pathogens by the U.S. Department of Health Continue reading
Researchers have debated for more than two decades the likely impacts, if any, of global warming on the worldwide incidence of malaria, a mosquito-borne disease that infects more than 300 million people each year.
Now, University of Michigan ecologists and their colleagues are reporting the first hard evidence that malaria does—as had long been predicted Continue reading
A new Defense Advanced Research Projects Agency (DARPA) program seeks technology that may make ultraviolet-based laser detection equipment for chemical and biological defense more readily available in the field.
Raman spectroscopy uses lasers to measure molecular vibrations to quickly and accurately identify unknown substances. Ultraviolet Continue reading
For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published this week in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases.
According to senior author Sina Bavari Continue reading
The Pentagon Force Protection Agency, Chemical, Biological, Radiological, Nuclear, & Explosive (CBRNE) Directorate is seeking proposals for provision of External Modeling System (EMS) support services.
The services include measuring complex winds in environments with dense buildings and complex terrain, high-quality sensing of the Continue reading
The U.S. Department of Defense recently issued a Request for Information (RFI) to conduct market research for manufacturing capabilities for a nerve agent pretreatment for use by military personnel.
The military currently procures a pretreatment for use prior to exposure to the chemical nerve agent soman, as part of Soman Nerve Agent Continue reading
BioCryst Pharmaceuticals, Inc. this week announced the online publication in the journal Nature of extensive laboratory and nonclinical characterizations of broad-spectrum antiviral BCX4430, including efficacy results in animal models of infection with Marburg virus and Ebola virus.
The Nature publication Continue reading
Immune system defenses against dangerous bacteria in the gut can be breached by turning off a single molecular switch that governs production of the protective mucus lining our intestinal walls, according to a study led by researchers at Yale, the University of British Columbia, and the Weizmann Institute of Science. Continue reading
Edgewood Chemical Biological Center (ECBC) is soliciting proposals to design and build a portable prototype Chemical Fingerprint Identification Systems (CFIS) that can identify trace levels of exogenous materials contained within fingerprints.
The goal of CFIS is to improve the capability to non-invasively, non-destructively Continue reading
Scientists at The Scripps Research Institute (TSRI) have mapped key elements of a severe immune overreaction—a “cytokine storm”—that can both sicken and kill patients who are infected with certain strains of flu virus.
Their findings also clarify the workings of a potent new class of anti-inflammatory compounds that prevent this immune overreaction Continue reading