Thursday, May 19, 2022
News on Pathogens and Preparedness
Global Biodefense
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe
No Result
View All Result
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe
No Result
View All Result
Global Biodefense
No Result
View All Result
Home Biodetection

Licensing Opportunity: Rapid Ultrasensitive Assay for Detecting Prions

by Global Biodefense Staff
September 17, 2020
Licensing Opportunity: Rapid Ultrasensitive Assay for Detecting Prions

Image credit: Jake Berenguer

Prion diseases are neurodegenerative diseases of great public concern. Currently, there are no tests that can accurately and economically detect low concentrations of prions in patients.

A new technology developed by the National Institutes for Allergy and Infectious Diseases (NIAID) enables rapid and economical detection of sub-lethal concentrations of prions in a sample by using recombinant normal prion protein (rPrP-sen) as a marker.

Specifically, prions in a sample seed the polymerization of rPrP-sen, and polymerized rPrP-sen is detected. This assay differs from the protein-misfolding cyclic amplification assay (PMCA) as it enables the effective use of rPrP-sen and does not require multiple amplification cycles.

This technology can be combined with additional prion-detection technologies to further improve the sensitivity of the assay. This assay has been successfully used to detect prions in brain tissue or cerebral spinal fluid from humans (variant CJD), sheep (scrapie), cattle (bovine spongiform encephalopathy), and deer (chronic wasting disease).

To learn more, please visit NIAID Tech Transfer or contact Jeffrey T. Thruston, J.D., M.S., (301) 594-5179; jeffrey.thruston@nih.gov.

Tags: BiotechnologyBovine Spongiform EncephalopathyChronic Wasting DiseaseCreutzfeldt-Jakob DiseaseEditor PickOpportunitiesPrions

Related Posts

NIH to Further Invest in Point-of-Care Technologies Research Network
Biodetection

NIH to Further Invest in Point-of-Care Technologies Research Network

May 10, 2022
Where is Testing Needed Most During Pandemic Surges? WVU Researchers Develop Machine Learning Prediction Tools
Biodetection

Where is Testing Needed Most During Pandemic Surges? WVU Researchers Develop Machine Learning Prediction Tools

May 6, 2022
Rapid COVID-19 PCR Test Developed at Northwestern Receives FDA Emergency Use Authorization
Biodetection

Rapid COVID-19 PCR Test Developed at Northwestern Receives FDA Emergency Use Authorization

March 19, 2022
Bruker Enables High-Throughput Multiplex HTS  in Support of Drug Discovery
Biodetection

Bruker Enables High-Throughput Multiplex HTS in Support of Drug Discovery

February 7, 2022
Load More

Latest News

NIH to Further Invest in Point-of-Care Technologies Research Network

NIH to Further Invest in Point-of-Care Technologies Research Network

May 10, 2022

How a COVID-19 Infection Spurs Antibodies Against Common Colds

May 8, 2022
Hospitals Resilience to Extreme Events: One-Third of Staff May Be Lost During a Disaster

Hospitals Resilience to Extreme Events: One-Third of Staff May Be Lost During a Disaster

May 6, 2022
Where is Testing Needed Most During Pandemic Surges? WVU Researchers Develop Machine Learning Prediction Tools

Where is Testing Needed Most During Pandemic Surges? WVU Researchers Develop Machine Learning Prediction Tools

May 6, 2022

Subscribe

  • About
  • Contact
  • Privacy
  • Subscribe

© 2022 Stemar Media Group LLC

No Result
View All Result
  • Featured
  • COVID-19
  • Funding
  • Directory
  • Jobs
  • Events
  • Subscribe

© 2022 Stemar Media Group LLC