In This Edition

‘Could This Be COVID-19?’ A Seattle Doctor on the Frontlines

Inside, as usual, patient beds are near capacity, and the emergency department is filled with not only the usual mix of patients with trauma, […]…

In Pictures: DoD Airlifts Swabs for COVID-19 Testing from Italy to Memphis

Approximately 500,000 testing swabs and supplies were flown by Air Mobility Command on March 19-20 from Aviano Air Base, Italy, to the FedEx hub […]…

Why Don’t We Have Drugs to Treat COVID-19 and How Long Will It Take to Develop Them?

SARS-CoV-2 – the coronavirus that causes the disease COVID-19 – is completely new and attacks cells in a novel way. Every virus is different […]…

Study from American Journal of Gastroenterology Reveals Diarrhea is a Prominent Symptom of COVID-19

Digestive symptoms are common in COVID19, occurring as the chief complaint in nearly half of patients presenting to hospital according to a new descriptive, […]…

Senator Murray Asks Government Watchdog to Investigate Novel Coronavirus Testing Missteps

U.S. Senator Patty Murray (D-WA), ranking member of the Senate Health, Education, Labor, and Pensions (HELP) Committee has called for an investigation into the […]…

Ibuprofen and COVID-19 Symptoms – Here’s What You Need to Know

There’s been some confusion recently on whether we should or shouldn’t take ibuprofen to treat symptoms of COVID-19 – especially after the World Health […]…

Sequencing the DNA of Patients Screened for Coronavirus Might Save Lives

Scientists should start sequencing the genomes of coronavirus patients. We should look for DNA differences between patients who are severely affected and those with […]…

Why Are There So Few COVID-19 Cases in Russia and Africa?

Since the COVID-19 pandemic began in Wuhan, China in December 2019, we have seen the virus spread to over 160 countries. Several countries have […]…

New Coronavirus SARS-CoV-2 Stable for Hours to Days on Surfaces

The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces, according to a new […]…

FDA Pandemic Response: States Can Now Approve COVID-19 Diagnostics, Serology Testing

The FDA today took unprecedented measures to expand coronavirus disease 2019 (COVID-19) diagnostics testing capacity by modifying policy originally issued on Feb. 29 which addresses laboratories […]…

Operation 50/50: List of Women Health Security Experts Now Available

Women in Global Health (WGH), and Women of Color Advancing Peace and Security (WCAPS) have partnered to crowdsource a list of female health security […]…

What Lessons Can the US Learn from Japan and South Korea for Combating Coronavirus?

On January 20, the World Health Organization (WHO) declared the spread of COVID-19, the disease caused by the new coronavirus SARS-CoV-2, which emerged in […]…

Caught Flat-Footed: How the U.S. Can Now Rally a Response Against Coronavirus

It’s always been a question of when, and not whether, humanity would face another challenge on the scale of the 1918 flu pandemic. The […]…

Soldiers Lend Language Skills to Help Washington State Translate Coronavirus Safety Messages

More than a dozen linguists assigned to the 341st Military Intelligence Battalion translated life safety and preparedness messages into multiple languages during February’s drill […]…

Using Antibodies from COVID-19 Survivors to Protect Healthcare Workers and Patients

Countries fighting outbreaks of the novel coronavirus disease COVID-19 should consider using the antibodies of people who have recovered from infection to treat cases […]…

Chasing the Antidote for Deadly Nerve Agents

In the most comprehensive, structure-based approach to date, a team of scientists may have discovered a new family of antidotes for certain poisons that […]…

The American Red Cross is asking for healthy, eligible individuals who are feeling well to give blood or platelets. This helps maintain a sufficient blood supply and prevent shortages as COVID-19 coronavirus cases rise in the U.S. People can make an appointment to donate blood by using the Red Cross Blood Donor App, visiting RedCrossBlood.org or calling 1-800-RED CROSS (1-800-733-2767). Type O and platelet donations are especially needed right now.


Headline News

Coronavirus Pandemic Bond Payouts Likely to Be Held Up By Fine Print

USAMRIID: America’s Key Lab for Fighting Infectious Diseases Has Become a Pentagon Backwater

How Did Florida Hire 100 Epidemiologists in a Weekend?

US Authorities Failing to Conduct Contact Tracing, a Cornerstone of Outbreak Response

Hotel Influenza: Research Heats Up on Universal Flu Vaccines

NASA Enacts Stage 2 Pandemic Response Posture


Biosecurity + Biodefense Jobs

Biologist – HHS/ASPR/BARDA

This position is located in the Department of Health And Human Services, Office of the Secretary of Health and Human Services, Office of Biomedical […] More

Technical Reachback Epidemiologist

Description Applied Research Associates, Inc. has an immediate opportunity for an epidemiologist to provide subject matter expert advice and decision support to the Defense […] More

Epidemic Intelligence Service Fellowship Class of 2021

EIS is a highly competitive, 2-year post-graduate fellowship in applied epidemiology. This CDC program, established in 1951, is a unique combination of on-the-job-learning and […] More

Evaluation Specialist, Neglected Tropical Diseases

The Evaluation Specialist will provide qualitative, quantitative, and mixed methods guidance for evaluation and implementation research activities for RTI’s neglected tropical disease programming (including, […] More

Deputy Director – Ebola Response Operations

The Deputy Director, Operations- Ebola Response (DDO) oversees the country program’s critical support functions: administration, human resources, supply chain and security, ensuring that all the […] More

Associate Program Officer, Polio, Eastern Mediterranean Region

As a key member of the Polio EMR (Eastern Mediterranean Region) team, the Associate Program Officer (APO), will partner closely with the Deputy Director […] More

Journal Watch

SARS-CoV-2 Infection in Children – NEJM

Virus Shedding in Rhesus Macaques Innoculated with SARS-CoV-2

Lopinavir-Ritonavir Does Not Offer Substantial Benefit in Severe COVID-19

Serological Assay to Detect SARS-CoV-2 Seroconversion in Humans

The Proximal Origin of SARS-CoV-2

LJI Scientists Identify Potential Targets for Immune Responses to SARS-CoV-2

COVID-19 and Italy: What Next?

SOCMED Highlights




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Superbugs & Superdrugs 2020

Due to ongoing concerns over COVID-19 this conference is now available with remote access only

30-31 MARCH 2020

SMi invites you to join an international gathering of industry experts sharing their experience and expertise on the challenges & solutions to antimicrobial resistance.

LEARN MORE + REGISTER >>


Contracts, Grants + Innovation Challenges

Mar: 29: Pandemic Response Hackathon Rapid teaming of public health professionals alongside the technology community’s talent to contribute to the world’s response to COVID-19.

Mar 31: EZ BAA Deadline: Novel Coronavirus Rapid Diagnostic Concise abstract submissions due for BARDA development funding of SARS-CoV-2 molecular diagnostics.

Apr 6: Influenza Data Processing and Outreach Contract proposals due for the Influenza Data Processing and Communication Center (iDPCC).

Apr 7: CEPI-EDCTP Seeks Proposals for Lassa Virus Vaccines Applications invited for large-scale collaborative projects which include one or more clinical trials (phase II to III) aiming to accelerate the clinical development of Lassa candidate vaccines.

Apr 9: Radiation/Nuclear Medical Countermeasures Development Supports MCMs to mitigate and/or treat tissue injuries resulting from exposure to ionizing radiation

Apr 9: Therapeutic Products for Biodefense, AMR Infections, and Emerging Infectious Diseases Supports development of promising new therapeutics to address infections caused by NIAID Category A, B, and C priority pathogens and select bacterial and fungal infections.

Apr 9: Advanced Development of Diagnostics for Biothreats and EID BAA topic supports development of novel, rapid sample-to-answer candidate diagnostic products that will address biodefense and pandemic preparedness.

Apr 24: JLABS @ Washington DC Innovations for Pediatric Influenza Intervention Innovators within the fields of pediatric oncology, pediatric surgery and influenza are invited to submit innovative ideas for grant funding, use of bench equipment and J&J mentorship at JLABS for 1 year.

Apr 30: EZ-BAA for COVID-19 Rapid Diagnostic BARDA rapid development funding of COVID-19 molecular diagnostics – must utilize platforms already cleared by the FDA.

Apr 30: BARDA BAA Medical Diagnostics and Countermeasures for SARS-CoV-2 This BAA amendment seeks biomedical and biopharma solutions to the immediate COVID-19 pandemic.

May 4: Global Health Security Partnerships – Lab Capacity Building CDC grant program to strengthen lab workforce, improve biorisk management, outbreak response globally.

Jul 2: NIBIB Technology Accelerator Challenge: Handheld Diagnostics Anticipated to be released this month, this innovation competition will spur design and development of non-invasive, handheld, digital diagnostic devices that will target anemia, sickle cell disease, malaria, and other blood-related diseases.

Industry + Partner News

Cepheid Receives Emergency Use Authorization from FDA for Rapid SARS-CoV-2 Test

First Rapid, Point-of-Care and Near-Patient Molecular Test for Detection of Virus that Causes COVID-19 Cepheid today announced it has received Emergency Use Authorization (EUA) […] More

Ventec Life Systems and GM Collaborate on Ventilator Production Surge

Ventec Life Systems and GM in cooperation with StopTheSpread.org, the nation’s coordinated private sector response to the COVID-19, are collaborating to enable Ventec to […] More

Canon Medical to Develop Rapid Genetic Testing System for Novel Coronavirus (COVID-19)

Canon Medical Systems announced the start of development of a rapid genetic testing system for the novel coronavirus (COVID-19). This project is part of […] More

Ridgeback Biotherapeutics and DRIVE Partner to Develop Clinical Stage Coronavirus Treatment

Ridgeback Biotherapeutics and Drug Innovations at Emory (DRIVE) LLC, a not-for-profit biotechnology company wholly owned by Emory University, today announced a collaboration to rapidly […] More

GenMark Receives FDA EUA for ePlex SARS-CoV-2 Test

GenMark Diagnostics, Inc. today announced that the U.S. Food and Drug Administration (FDA) has issued Emergency Use Authorization (EUA) for the company’s ePlex SARS-CoV-2 […] More

Abbott Receives FDA Emergency Use Authorization and Launches Test to Detect Novel Coronavirus

Abbott announced today that the U.S. Food and Drug Administration has issued Emergency Use Authorization (EUA) for the company’s molecular test for novel coronavirus […] More

Regeneron Makes Progress on Novel COVID-19 Antibody Program

Regeneron Pharmaceuticals, Inc. today announced the latest progress in its efforts to discover and develop a novel multi-antibody cocktail that can be administered as […] More

PharmaJet Receives $9.6 Million Dollar Award to Support Next-Generation Needle-Free Delivery Devices

PharmaJet has announced that it received a $9.6 million dollar contract award from the Joint Science and Technology Office of the U.S. Defense Threat […] More

Novel High-Density Microarray Patch Can Deliver Vaccines Directly to the Skin

Vaxxas, a clinical-stage biotechnology company commercializing a novel vaccination platform, today announced the publication in the journal PLoS Medicine of groundbreaking clinical research indicating […] More

FDA Policy Change Clears Path for Wider Use of Co-Diagnostics’ Coronavirus Test

Molecular diagnostics company Co-Diagnostics, Inc. announced today that a new FDA policy released last night aimed at expediting the availability of COVID-19 diagnostics will […] More

Pfizer and BioNTech to Co-Develop Potential COVID-19 Vaccine

Companies will jointly develop BioNTech’s mRNA-based vaccine candidate BNT162 to prevent COVID-19 infection. Pfizer Inc. and BioNTech SE today announced that the companies have […] More

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Headlines

Coronavirus Pandemic Bond Payouts Likely to Be Held Up By Fine Print

Investors are looking at big losses in two “pandemic bonds,” issued by the World Bank’s International Bank for Reconstruction and Development (IBRD) in 2017, which […] More

USAMRIID: America’s Key Lab for Fighting Infectious Diseases Has Become a Pentagon Backwater

At the White House briefing Wednesday on efforts to combat COVID-19, Defense Secretary Mark Esper said that he had just visited the U.S. Army […] More

How Did Florida Hire 100 Epidemiologists in a Weekend?

Last week, Florida health officials found themselves overwhelmed. The state’s disease experts were working around the clock to trace the rapidly spreading coronavirus, and […] More

US Authorities Failing to Conduct Contact Tracing, a Cornerstone of Outbreak Response

If the US forgoes contact tracing in favour of aggressive social-distancing measures alone, the country risks the outbreak worsening, and lockdown measures such as […] More

Influenza Virus

Hotel Influenza: Research Heats Up on Universal Flu Vaccines

A universal flu vaccine has eluded scientists for decades. Unlike other viruses, influenza has a rapid-fire mutation rate and thousands of different strains, which […] More

NASA Enacts Stage 2 Pandemic Response Posture

NASA leadership announced on Mar. 14 enactment of Stage 2 of the agency’s Response Framework for the novel coronavirus (COVID-19) crisis. In Stage 2, […] More


PODCASTS + VIDEOS

Coronavirus #555 Science for the People – guests on this episode are Dr Jason Kindrachuk and Kelly Hills

Don’t Touch Your Face: Lockdown Foreign Policy Daily podcast covering all aspects of COVID-19

Tracking COVID-19 Harverd T.H.Chan School of Public Health On-demand video recording of recent forum.


Essential Research

SARS-CoV-2 Infection in Children – NEJM

In order to determine the spectrum of disease in children, researchers evaluated children infected with SARS-CoV-2 and treated at the Wuhan Children’s Hospital. Of […] More

Virus Shedding in Rhesus Macaques Innoculated with SARS-CoV-2

Certain aspects of the pathogenesis of SARS-CoV-2 can only be studied in detail in animal models, where repeated sampling and tissue collection is possible. […] More

Lopinavir-Ritonavir Does Not Offer Substantial Benefit in Severe COVID-19

A total of 199 patients with laboratory-confirmed SARS-CoV-2 infection underwent randomization; 99 were assigned to the lopinavir–ritonavir group, and 100 to the standard-care group. […] More

Serological Assay to Detect SARS-CoV-2 Seroconversion in Humans

We currently lack serological assays suitable to specifically detect SARS-CoV-2 antibodies, of critical importance to determine seroprevalence in a given population, define previous exposure […] More

The Proximal Origin of SARS-CoV-2

Identifying the closest viral relatives of SARS-CoV-2 circulating in animals will greatly assist studies of viral function. The genomic features described here may explain […] More

LJI Scientists Identify Potential Targets for Immune Responses to SARS-CoV-2

Within two months, SARS-CoV-2, a previously unknown coronavirus, has raced around globe, infecting over a 100,000 people with numbers continuing to rise quickly. Effective […] More


FEATURED EVENTS

Mar: 24 The Role of Digital Health Technologies in Drug Development (Webcast)

The National Academies Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health will host a public workshop via webcast on Zoom on 24 Mar. Learn more.

Mar 24: World TB Day 2020

As we mark this day of Tuberculosis awareness, take a look at some of the latest research highlights here.

Mar 24-25 BIO Coronavirus Collaboration Initiative Virtual Summit

BIO is hosting a virtual summit to help companies working on COVID-19 treatments, diagnostics and vaccines to come together to discuss challenges and opportunities with government officials and other stakeholders. Learn more

Mar 25: Responding to COVID-19 Webinar: The Science of Social Distancing

The webinar will feature a panel of expert speakers, including: Nancy Messonnier, Marc Lipsitch, Mitch Stripling, and Howard Markel. Learn more

Mar 25: A Comprehensive Introduction to Medical Simulation (Webinar)

Join HDIAC on Wednesday, March 25, from 1200 to 1300 EDT for a live webinar presentation titled “A Comprehensive Introduction to Medical Simulation”. Learn more

Mar 26: Policy vs. Pandemics: Polarization and Public Health emergency Preparedness (Webcast)

George Mason University Schar School of Policy and Government will host this no-fee webinar event, “Policy vs. Pandemics: Polarization and Public Health Emergency Preparedness,” on March 26. Learn more

Mar 30-31: Superbugs + Superdrugs 2020 (Webcast)

Bringing industry leaders together to discuss the strategies in place that reduce AMR, evaluate the role pharmaceutical companies and funding bodies play in reducing AMR, learn about new diagnostics approaches to identify AMR and consider novel candidates and alternatives to anti-microbials. Register now

26 Mar: APIC | AIHA Webinar – Ventilation, Surface Disinfection and PPE Considerations for the IP and IH

Town-hall style webinar to address occupational health and safety professionals’, industrial hygienists’ and infection preventionists’ questions about ventilation, surface disinfection, respirators, construction issues, occupational health and safety during the COVID-19 pandemic. Learn more

VIEW ALL EVENTS

May 28-29: Critical Public Health Value of Vaccines in the Age of Pandemics

The National Academies of Sciences, Engineering, and Medicine Board on Global Health will host a 1.5-day public workshop May 28-29 that will examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy globally, and the multidimensional drivers and impacts of declining vaccine confidence. Learn more

Jun 10-11: Joint Civil + DoD CBRN Symposium (New Dates)

An annual gathering of the most respected minds in the CBRN defense community, including operational leaders, intelligence providers, key policymakers and solution providers from Industry and Academia. Register now

Jun 28 – Jul 2 CSTE Annual Conference

The CSTE Annual Conference connects more than 1,700 public health epidemiologists from across the country and will include workshops, plenary sessions with leaders in the field of public health, oral breakout sessions, roundtable discussions, and poster presentations. Learn more

Aug 21-26 Preparedness Summit 2020
(New Dates)

Join experts and stakeholders from across public health, healthcare, disaster relief, emergency management, and related fields nationwide. Learn more

Dec 15-17 SYNChronicity 2020 – National Conference for HIV, HCV, STI and LGBTQ Health (New Dates)

Brings together medical professionals, service providers, government officials, and health advocates to sync effective approaches to address HIV, HCV, STI, and LGBTQ health in the changing and dynamic health care landscape. Learn more

20-23 Apr 2021 ABSA’s 1st Biosecurity Symposium (New Dates)

Due to the COVID-19 pandemic, ABSA’s 1st Biosecurity Symposium has been rescheduled and will now take place 20-23 April 2020 in Minneapolis, MN. Learn more


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Latest News from Global Biodefense

FDA-ARGOS SARS-CoV-2 Reference Grade Sequence Data Now Available

FDA-ARGOS SARS-CoV-2 Reference Grade Sequence Data Now Available

In response to the COVID-19 pandemic, the FDA—in collaboration with the Centers for Disease Control and Prevention (CDC), the Biodefense and Emerging Infections Research […]…

Designing Face Shields to Protect Medical Staff During Critical Supply Shortages

Designing Face Shields to Protect Medical Staff During Critical Supply Shortages

The COVID-19 pandemic has created an unprecedented need to provide personal protective equipment (PPE) for hospital staff. A team of Montreal medical experts has […]…

Tests in Engineered Human Tissues Show hrsACE2 Drug Blocked Early Stages of SARS-CoV-2 Infection

Tests in Engineered Human Tissues Show hrsACE2 Drug Blocked Early Stages of SARS-CoV-2 Infection

An international team led by University of British Columbia researcher Dr. Josef Penninger has found a trial drug that effectively blocks the cellular door […]…

JPEO-CBRND, BARDA Partner with SAb Biotherapeutics to Develop COVID-19 Therapeutic

JPEO-CBRND, BARDA Partner with SAb Biotherapeutics to Develop COVID-19 Therapeutic

A therapeutic to treat novel coronavirus disease 2019 (COVID-19) is moving forward in development through a partnership announced Apr. 1 between BARDA, the Department of […]…

Health Security Today – 1 April 2020

Health Security Today – 1 April 2020

Contents FEATUREDFDA, NIH, Veteran Affairs Partner with America Makes for 3D Printing Innovations During Pandemic ResponseMapping Risks to the Drug Supply Chain During COVID-19 […]…

USAMRIID Resumes Full Operations Following Federal Select Agent Program Reinstatement

USAMRIID Resumes Full Operations Following Federal Select Agent Program Reinstatement

Researchers at the U.S. Army Medical Research Institute of Infectious Diseases continue to work on medical countermeasures for the novel coronavirus as part of […]…

Diagnostic Hoax: FDA Has Not Announced EUA for Bodysphere 2-Min Test

Diagnostic Hoax: FDA Has Not Announced EUA for Bodysphere 2-Min Test

Reuters published a short report based on a poorly written press release on BusinessWire (since removed) from an unverified company claiming to have received […]…

Preventing COVID-19 From Overtaking Nursing Homes Requires Spending Money and Improving Infection Control

Preventing COVID-19 From Overtaking Nursing Homes Requires Spending Money and Improving Infection Control

At least 11 people have died from COVID-19 in New Orleans nursing homes in the past week, just after the deaths at a Seattle […]…

Cue Health Awarded Federal Contract for 25-Minute Nasal Swab COVID-19 Test

Cue Health Awarded Federal Contract for 25-Minute Nasal Swab COVID-19 Test

The Biomedical Advanced Research and Development Authority (BARDA) and Cue Health will collaborate under a new contract announced today to accelerate the development, validation, […]…

Duke Starts Innovative Decon of N95 Masks Using Vaporized Hydrogen Peroxide to Alleviate Shortages

Duke Starts Innovative Decon of N95 Masks Using Vaporized Hydrogen Peroxide to Alleviate Shortages

Facing a critical shortage of N95 face masks that block the coronavirus, Duke Health research and clinical teams have confirmed a way to use […]…

FDA, NIH, Veteran Affairs Partner with America Makes for 3D Printing Innovations During Pandemic Response

FDA, NIH, Veteran Affairs Partner with America Makes for 3D Printing Innovations During Pandemic Response

The federal government this week took steps to formalize a collaboration framework to facilitate regulatory and basic science innovation with 3D printing technologies to […]…

Pregnant in a Time of Coronavirus – The Changing Risks and What You Need to Know

Pregnant in a Time of Coronavirus – The Changing Risks and What You Need to Know

“So, being pregnant and delivering in a pandemic … what’s that gonna look like?” That question, sent to me by a colleague who is […]…