The Ministry of Health of Guinea has reported a cumulative total of 143 clinically compatible cases of Ebola virus disease (EVD), of which 54 are laboratory confirmed by PCR. The total number includes 86 deaths (CFR 60%). New cases have been reported from Conakry, Guekedou and Macenta; 23 patients are currently in isolation units. The date of onset of the most recent laboratory confirmed case is 3 April.
The numbers represent the most recent update issued by the World Health Organization (WHO) on 5 April.
There has been no increase in the number of affected health-care workers (HCW) from the 14 reported previously, including 8 deaths; 11 of the affected HCWs are laboratory confirmed cases. Sixteen of the 86 deaths overall are laboratory confirmed, 65 are classified as probable cases and 5 as suspected cases.
Case investigation and contact tracing are continuing, with 623 contacts requiring medical follow-up; this includes 74 new contacts identified on 3 April while 49 have been released from observation as they have remained well after the maximum incubation period for EVD of 21 days following the last exposure to a case.
Liberia has reported 18 suspected and 2 confirmed cases of EBV, including 7 deaths. 46 contacts have been placed under medical observation. Counties of concern for EVD in Liberia include Lofa, Bong, Nimba, Margibi and Montserrado.
There has been no change in the situation in Sierra Leone following the deaths of 2 probable cases of EVD in one family who died in Guinea and their bodies repatriated to Sierra Leone. The office of the Chief Medical Officer (CMO) is coordinating all operations involving suspected cases of Ebola as well as the follow-up investigations. Enhanced surveillance and public education activities are continuing.
The Metabiota Laboratory in Kenema, Sierra Leone, will install Real-Time Zaire ebolavirus-specific PCR, a pan-filo PCR, Lassa virus PCR, yellow fever and Marburg virus PCRs among other assays. This technology is being transferred from its laboratory in Kenema, Sierra Leone. Metabiota will also provide training to laboratory staff in Liberia.
The Ministry of Health of Mali has reported 4 patients suspected to have a viral haemorrhagic fever who presented for health care in Sibiribougou, Koulikoro Region of Mali. Two of the suspected cases had travelled from Guinea. The patients were placed in isolation pending epidemiological investigations and laboratory testing. Contact tracing is underway. Clinical samples have been sent to the Centers for Disease Control and Prevention (CDC), Atlanta, United States, for testing. Epidemiological surveillance is being enhanced on the ground and Rapid Response Teams are being mobilised to identify and treat suspected cases should others present. An isolation unit has been prepared in Bamako and units are also being installed in other locations. Information hotlines are being made available to the public.