The U.S. military is seeking innovative ideas for development of technologies for chemical and biological defense applications under a Broad Agency Announcement (BAA) released this week by the Defense Threat Reduction Agency (DTRA) and the Joint Science and Technology Office for Chemical and Biological Defense (JSTO-CBD).
The requirements focus on the areas of diagnostics, detection, and disease surveillance; translational medicine; advanced and emerging threats; physical science and technology; and information systems. The overall goal is to identify and select science and technology projects that can be transitioned to joint acquisition programs.
Proposals are encouraged that span a wide spectrum of possible technical and business solutions in response to specific topics including:
Single Cell Biomarker Expression Methods and Analysis, Point-of-Need Diagnostics
Host-Based Biomarker/Assay Development
Bioagent Infection of In Vitro Organ Models to Develop Companion Diagnostics
Next-Generation Analytical Capabilities for Biosurveillance
Biosurveillance Ecosystem Analytics
Enhancing the Baseline – Data Collection and Aggregation
Alternative Manufacturing Processes for Recombinant Human Butyrylcholinesterase
Pretreatments for Chemical Nerve Agent Exposure
Centrally Active Nerve Agent Treatment Systems (CANATs)
Atmospheric Persistence of CB Particulate and Aerosol Threats
Predictive Toxicology Tools for Enabling Rapid Countermeasure Development
Methods for Rapid Prediction of Agent-Substrate Interactions
Novel vaccines for Burkholderia pseudomallei and Burkholderia mallei
Vaccine Candidates for Type A Francisella tularensis,
Vaccine Candidates for Q Fever
Antibody-based Prophylactic Protection against Viral Pathogens
Drug Discovery and Development for Encephalitic Alphavirus Infections
Antimicrobial Development for Burkholderia pseudomallei and Multi-Drug Resistant (MDR) Strains of Bacillus Anthracis, YersiniaPestis, and Francisella Tularensis
CB Mobile Sensing Technology Demonstration
Additive Manufacturing Replenishment of Expendable Chem/Bio Sensors
Rapid Mitigation of the Threat of Bulk Chemical Weapon Material in the Field
DTRA states that new or emerging requirements may necessitate future amendment of the Broad Agency Announcement to include additional topics.
Further details are available under Solicitation Number: HDTRA1-14-CHEM-BIO-BAA. Initial proposals are due March 20, 2013.
