National Vaccine Trial Will Focus on Those with History of Severe Allergies or Mast Cell Disorder
In a carefully controlled clinical trial, Michigan Medicine researchers will examine whether participants who are highly allergic or have a ...
Tag: Clinical Trials
Trial of Novel MIS-C Therapy Underway at Medical University of South Carolina
A team of MUSC Children's Health pediatricians was the first in the nation to enroll patients with multisystem inflammatory syndrome ...
Rigel Awarded $16.5 Million from DoD for Phase 3 Trial of Fostamatinib in COVID-19 Patients
Rigel Pharmaceuticals, Inc. announced on Jan. 29 it has been awarded $16.5 million by the U.S. Department of Defense's (DOD) Joint Program ...
Why Combining the Oxford COVID-19 Vaccine with Russia’s Sputnik V Could Make It More Effective
When the efficacy of the Oxford/AstraZeneca vaccine was announced in late 2020, there was some confusion. The overall efficacy of ...
DoD Awards Funding to Pulmotect to Study Repurposed PUL-042 Against COVID-19
The Department of Defense (DOD) awarded a $6 million agreement to Pulmotect, Inc., a clinical-stage biotechnology company, to execute two ...
Large Clinical Trial in Africa Tests Treatments for Mild and Moderate COVID-19 Cases
Thirteen African countries and an international network of research institutions have joined forces to launch the largest COVID-19 clinical trial ...
Oxford-AstraZeneca COVID-19 Vaccine: Cheaper and Doesn’t Require Supercold Storage Quagmire
The biopharmaceutical company AstraZeneca has released data on what is now the third promising vaccine candidate against COVID-19 – and ...
Altimmune Poised to Begin Phase 1 Clinical Trial of Single-Dose Intranasal COVID-19 Vaccine
Altimmune Inc. has submitted an Investigational New Drug application to the U.S. Food and Drug Administration to commence a Phase ...
COVID-19 Vaccines Were Developed in Record Time – But are These Game-Changers Safe?
There are now two COVID-19 vaccines that, at least according to preliminary reports, appear to be 94.5% and 95% effective. ...
New Study Casts Doubt on Benefit of Tocilizumab for Worsening Cases of COVID-19
The drug tocilizumab (Actemra) does not reduce the need for breathing assistance with mechanical ventilation or prevent death in moderately ...
Hydroxychloroquine as Pre-Exposure Prophylaxis: Randomized Clinical Trial Shows No Benefit
U of M trial shows hydroxychloroquine does not prevent COVID-19 in health care workers University of Minnesota Medical School physician ...
BARDA Awards Medical Countermeasures Clinical Studies Network Contracts
New contract awards by the Biomedical Advanced Research and Development Authority (BARDA) will support three integrated components of the Medical ...
Autoimmune-Like Antibody Response Linked with Severe COVID-19
In the earliest days of the pandemic, many immunologists, including me, assumed that patients who produced high quantities of antibodies ...
Pipeline COVID-19 Vaccines Not Affected by ‘G-Strain’ Mutation
In a new study, researchers from the Dangerous Pathogens Team at CSIRO conclude vaccines currently under development for COVID-19 should ...
NIH Expands COVID-19 Convalescent Plasma Clinical Trials
The National Institutes of Health (NIH) today announced it is expanding enrollment in two existing clinical trials to further evaluate ...
WHO Meta-Analysis: Corticosteroids Save Lives of Critically Ill COVID-19 Patients
Readily available drugs, which dampen the runaway inflammatory response in patients severely ill with COVID-19, save lives, according to evidence ...
Lessons From Hydroxychloroquine: Improving FDA’s Authorization and Approval Process
On March 28, the Food and Drug Administration (FDA) exercised its Emergency Use Authorization (EUA) authority to allow the use ...
Urgent Phase I/II Clinical Trial Funding to Repurpose Existing Therapeutics to Treat COVID-19
The National Institutes of Health has issued an urgent funding opportunity announcement to invite applications to repurpose existing therapeutic agents ...
NIAID-Led Study of COVID-19 mRNA Vaccine Supports Advance to Phase 3 Human Trials
Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the ...
Moderna’s COVID-19 Vaccine Generally Well Tolerated in Ongoing Phase 1 Trial
An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well ...
