Mosquito-Borne

Mosquito-borne infectious diseases—including viruses such as such as dengue, Zika, chikungunya, and West Nile—pose serious and evolving threats to global public health. Transmitted primarily by mosquito vectors like Aedes aegypti and Culex species, these viruses cause a range of clinical syndromes, from febrile illness and hemorrhagic disease to encephalitis and congenital anomalies.

Some, like Rift Valley fever and yellow fever, are formally recognized as biodefense-relevant pathogens by U.S. and international agencies due to their epidemic potential, zoonotic impact, and economic disruption. Others—Zika, chikungunya, and dengue viruses—are not classified as biodefense threats but are prioritized for epidemic preparedness under the WHO R&D Blueprint due to their widespread burden, lack of licensed therapeutics, and expanding geographic reach.

Climate change, urbanization, global travel, and shifting mosquito ecology are intensifying transmission risks. Addressing these challenges demands enhanced surveillance, diagnostic innovation, vaccine development, and integrated vector control strategies.

Explore our latest articles to stay informed on the evolving science, policies, and innovations shaping the global response to mosquito-borne infectious diseases.